Glass Label/Source Record

Effect of taurine on blood pressure: Meta-analysis

Significant reduction in systolic BP (-4.1 mmHg)

Zhang, M., Li, Y., Wang, H. / Hypertension Research / 2022DOI 10.1038/s41440-022-00881-0PubMed 35462591
Subjects
1
Use Types
4
Interpretation
Global source, local meaning.
Contested Uses
1
Revised Uses
1
Abstract

Background: Taurine has been proposed as a nutrient that may modestly lower blood pressure through vascular, renal, and autonomic effects. We conducted a systematic review and meta-analysis of randomized and controlled studies evaluating taurine supplementation in adults with normotension, prehypertension, or hypertension. Outcomes included systolic and diastolic blood pressure, study duration, dose, and adverse events. Across pooled trials, taurine was associated with a small but statistically significant reduction in systolic pressure, with a more variable effect on diastolic pressure. Benefits appeared greater in participants with elevated baseline blood pressure and in studies using multi-week supplementation. Heterogeneity reflected differences in dose, population, and co-interventions, but directionality was generally consistent. Taurine was well tolerated, with few discontinuations attributable to treatment. The findings suggest a plausible adjunctive role for taurine in blood pressure management, although larger trials are needed to clarify optimal dosing and clinical relevance.

Local Source Uses

Every indexed place this source is used

compound7 local uses
Taurine