Other
Other safety context
Overuse and load progressionMonitor
Rapid increases in running, cycling, or other repetitive aerobic load can exceed tissue tolerance even when intensity is moderate.
Human evidenceEnergy availability and recoveryInformational
Aerobic volume becomes harder to interpret when sleep, energy intake, illness, or recovery capacity are poor.
Mixed evidenceProgressive acclimationInformational
Exposure tolerance should be treated as an implementation variable; shorter and less intense sessions are more defensible starting contexts than maximal heat stress.
Mixed evidenceElderly individualsInformational
Endogenous synthesis and tissue levels may decline with age.
Human evidencePremature infantsInformational
Immature biosynthetic capacity; higher taurine requirements during development.
Clinical review